What is the Epirubicin hydrochloride?

Epirubicin hydrochloride is Orange-red crystalline solid, while it's Molecular Formula is C27H29NO11.HCl. Orange-red crystalline solid Cell-permeable anthracycline anti-tumor antibiotic

What is the CAS number for Epirubicin hydrochloride?

The CAS number of Epirubicin hydrochloride is 56390-09-1.

What is Epirubicin hydrochloride (56390-09-1) used for?

Epirubicin is a stereoisomer of the antitumor anthracycline doxorubicin that undergoes β-glucuronidation, which partially detoxifies the dose-limiting side effects that are present with doxorubicin. Compared to doxorubicin, epirubicin is equally cytotoxic to HeLa cells (ID50s = 9 μM). When used either alone or in combination therapies, epirubicin has been shown to demonstrate high rates of complete or partial remission in various cancers including advanced ovary, lymphomas, breast, pancreas, gastric, hepatocellular carcinoma, head and neck tumors, and colorectal.InChI:InChI=1/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17+,22-,27-/m0/s1

What is the Epirubicin hydrochloride?

Epirubicin hydrochloride is Orange-red crystalline solid, while it's Molecular Formula is C27H29NO11.HCl. Orange-red crystalline solid Cell-permeable anthracycline anti-tumor antibiotic

What is the CAS number for Epirubicin hydrochloride?

The CAS number of Epirubicin hydrochloride is 56390-09-1.

What is Epirubicin hydrochloride (56390-09-1) used for?

Epirubicin is a stereoisomer of the antitumor anthracycline doxorubicin that undergoes β-glucuronidation, which partially detoxifies the dose-limiting side effects that are present with doxorubicin. Compared to doxorubicin, epirubicin is equally cytotoxic to HeLa cells (ID50s = 9 μM). When used either alone or in combination therapies, epirubicin has been shown to demonstrate high rates of complete or partial remission in various cancers including advanced ovary, lymphomas, breast, pancreas, gastric, hepatocellular carcinoma, head and neck tumors, and colorectal.InChI:InChI=1/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17+,22-,27-/m0/s1

Product Class

56390-09-1

Product Name：Epirubicin Hcl
Molecular Formula：C₂₇H₂₉NO₁₁.HCl
Purity：99%
Molecular Weight：579.99

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Product Details:

CasNo： 56390-09-1

Molecular Formula： C₂₇H₂₉NO₁₁.HCl

Appearance： Orange-red crystalline solid

Buy Quality Epirubicin Hcl ,Top Purity 56390-09-1 Lowest Price

Molecular Formula:C27H29NO11.HCl
Molecular Weight:579.99
Appearance/Colour:Orange-red crystalline solid
Vapor Pressure:9.64E-28mmHg at 25°C
Melting Point:185 °C dec
Refractive Index:1.709
Boiling Point:810.3 °C at 760 mmHg
Flash Point:443.8 °C
PSA：206.07000
Density:1.61 g/cm³
LogP:1.50360

Epirubicin hydrochloride(Cas 56390-09-1) Usage

Description	Epirubicin HCl is a type of chemotherapy medication that belongs to the anthracycline class of drugs. It is the hydrochloride salt of the 4'-epi-isomer of doxorubicin, another anthracycline antineoplastic antibiotic. Epirubicin works by inhibiting the replication of cancer cells, disrupting their ability to copy DNA and produce RNA and proteins necessary for their growth and survival.
Chemical Properties	Orange-Red Crystalline Solid
Originator	Erbamont (Italy)
Uses	Epirubicin hydrochloride is utilized in the treatment of various types of cancers, including: Breast cancer: Epirubicin injection is often used in combination with other cancer medicines to treat breast cancer in patients who have undergone surgery to remove the tumor. It helps to destroy any remaining cancer cells and reduce the risk of cancer recurrence. Mammary, gastric, colorectal, pulmonary, and ovarian carcinomas: Epirubicin has demonstrated efficacy in the treatment of these cancers, either as a single agent or in combination with other chemotherapy drugs. Malignant lymphoma and melanoma: Epirubicin may also be used in the treatment of certain lymphomas, melanomas, and soft tissue sarcomas, either alone or in combination with other chemotherapy agents.
Brand name	Ellence(Pfizer);FARMORUBICIN.

InChI:InChI=1/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17+,22-,27-/m0/s1

56390-09-1 Relevant articles

Interaction of epirubicin HCl with surfactants: Effect of NaCl and glucose

N Erdi̇Nç，S Göktürk，M Tunçay

, Journal of Pharmaceutical Sciences 2010/5/17

The interaction of an antitumoural drug, Epirubicin HCl, with anionic (sodiumdodecylsulfate; SDS), cationic (cetyltrimethylammonium bromide; CTAB), and nonionic (t‐octylphenoxypolyethoxyethanol; TX‐100, polyoxyethylenesorbitanmonolaurate; Tween 20) surfactants has been studied by absorption spectra as a function of surfactant concentration ranging from the premicellar to postmicellar region.

Effects of Epigallocatechin Gallate on the Cytotoxicity of Epirubicin-HCl in Lung Cancer Cells

A Erdogan，A Ozkan

Letters in drug design & discovery

In this context, our study determined the most effective application sequence by evaluating the cytotoxic responses of epirubicin-HCl and EGCG according to the different application orders in A-549 cells (NSCLC). Methods: To demonstrate the apoptotic activity, we detected changes in mRNA ratios of Bax, a proapoptotic gene, and Bcl-2, an anti-apoptotic gene (Bax/Bcl2), as well as changes in the activity of caspase 3/7 enzyme.

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