• Product Name:Oxaliplatin
  • Molecular Formula:C8H14N2O4Pt
  • Purity:99%
  • Molecular Weight:397.29

Product Details:

CasNo: 61825-94-3

Molecular Formula: C8H14N2O4Pt

Appearance: White crystalline solid

Quality Manufacturer Supply Best Quality Oxaliplatin 61825-94-3 Efficient Transportation

  • Molecular Formula:C8H14N2O4Pt
  • Molecular Weight:397.29
  • Appearance/Colour:White crystalline solid 
  • Boiling Point:193.6oC at 760 mmHg 
  • Flash Point:75oC 
  • PSA:104.64000 
  • LogP:0.61450 

Oxaliplatin(Cas 61825-94-3) Usage


Oxaliplatin is a member of the platinum-based chemotherapeutic class of drugs. It is a platinum-containing DNA-crosslinking agent that induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein crosslinks. By inhibiting DNA and RNA synthesis and inducing apoptosis in cancer cells, oxaliplatin exerts its cytotoxic effects.

Chemical Properties

White Crystalline Solid


Bebiopharm (Switzerland)


Oxaliplatin is primarily used in the treatment of metastatic colorectal cancer, either as a standalone treatment or in combination with other chemotherapy drugs. It is effective in reducing tumor growth and improving survival outcomes in patients with advanced colorectal cancer. Oxaliplatin is typically administered intravenously, usually as part of a chemotherapy regimen. The dosage and frequency of administration may vary depending on the specific treatment protocol and the patient's individual characteristics.

Brand name

Eloxatin (Sanofi Aventis).

Biological Activity

Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Displays higher cytotoxicity and lower nephrotoxicity than analog cisplatin (cis-Diaminodichloroplatinum ) and shows antitumor activity in cell lines with acquired cisplatin resistance.


61825-94-3 Relevant articles

Oxaliplatin: A review of preclinical and clinical studies

E. Raymond 1, S.G. Chaney 2, A. Taamma 3, E. Cvitkovic 3 4

, Annals of Oncology Volume 9, Issue 10, October 1998, Pages 1053-1071

In phase I trials, the dose-limiting toxicity of oxaliplatin was characterized by transient acute dysesthesias and cumulative distal neurotoxicity, which was reversible within a few months after treatment discontinuation.

Cellular and Molecular Pharmacology of Oxaliplatin

Eric Raymond; Sandrine Faivre; Stephen Chaney; Jan Woynarowski; Esteban Cvitkovic

, Mol Cancer Ther (2002) 1 (3): 227–235.

In in vivo studies, oxaliplatin is active against breast, colon, and gastric cancer; renal cell carcinoma; and sarcoma (16). In addition, oxaliplatin has been tested in vitro and in vivo against cisplatin-resistant cell lines and tumor models, including human ovarian, lung, cervix, colon, and leukemia cell lines.

Phorbiplatin, a Highly Potent Pt(IV) Antitumor Prodrug That Can Be Controllably Activated by Red Light

Wang, Zhigang,Wang, Na,Cheng, Shun-Cheung,Xu, Kai,Deng, Zhiqin,Chen, Shu,Xu, Zoufeng,Xie, Kai,Tse, Man-Kit,Shi, Peng,Hirao, Hajime,Ko, Chi-Chiu,Zhu, Guangyu

, p. 3151 - 3165 (2019)

Selective activation of prodrugs within ...

Cytotoxicity and ROS production of novel Pt(IV)oxaliplatin derivatives with indole propionic acid

Tolan, Dina,Almotairy, Awatif Rashed Z.,Howe, Orla,Devereux, Michael,Montagner, Diego,Erxleben, Andrea

, p. 262 - 267 (2019)

The coordination of biologically active ...

Electrodrugs: An electrochemical prodrug activation strategy

Norman, Daniel J.,González-Fernández, Eva,Clavadetscher, Jessica,Tucker, Lulu,Staderini, Matteo,Mount, Andrew R.,Murray, Alan F.,Bradley, Mark

, p. 9242 - 9245 (2018)

The term electroceutical has been used t...

An intramolecular photoswitch can significantly promote photoactivation of Pt(iv) prodrugs

Chen, Shu,Deng, Zhiqin,Hirao, Hajime,Li, Cai,Wang, Zhigang,Xu, Zoufeng,Yao, Houzong,Zhou, Qiyuan,Zhu, Guangyu

, p. 6536 - 6542 (2021/05/31)

Selective activation of prodrugs at dise...

Stability, Reduction, and Cytotoxicity of Platinum(IV) Anticancer Prodrugs Bearing Carbamate Axial Ligands: Comparison with Their Carboxylate Analogues

Chen, Shu,Gunawan, Yuliana F.,Tse, Man-Kit,Yao, Houzong,Zhou, Qiyuan,Zhu, Guangyu

supporting information, (2020/08/24)

Platinum(IV) complexes containing carbox...

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