• Product Name:Levofloxacin Hemihydrate
  • Molecular Formula:2(C18H20FN3O4).H2O
  • Purity:99%
  • Molecular Weight:740.761

Product Details:

CasNo: 138199-71-0

Molecular Formula: 2(C18H20FN3O4).H2O

Appearance: pale yellow solid

Buy Quality Levofloxacin Hemihydrate,Hot Sale 138199-71-0 In Stock

  • Molecular Formula:2C18H20FN3O4*H2O
  • Molecular Weight:740.761
  • Appearance/Colour:pale yellow solid 
  • Vapor Pressure:6.7E-14mmHg at 25°C 
  • Melting Point:214-216 °C 
  • Boiling Point:571.5 °C at 760 mmHg 
  • Flash Point:299.4 °C 
  • PSA:84.24000 
  • Density:1.48 g/cm3 
  • LogP:1.48260 

Levofloxacin Hemihydrate(Cas 138199-71-0) Usage


Levofloxacin, in its hemihydrate form, is effective against a wide range of bacterial infections, making it a valuable tool in the treatment of various bacterial diseases. Levofloxacin hemihydrate is a formulation of the antibiotic levofloxacin that exists as a hemihydrate under ambient conditions.


Levofloxacin hemihydrate is commonly prescribed by healthcare professionals for the treatment of bacterial infections in various parts of the body, including respiratory, urinary, skin, and soft tissue infections, among others. It is an orally active antibiotic with broad-spectrum activity against both Gram-positive and Gram-negative bacteria. Levofloxacin is used to treat bacterial infections affecting various parts of the body and is also indicated for specific conditions such as anthrax infection after inhalational exposure and the treatment and prevention of plague, including pneumonic and septicemic plague.

Brand name

Iquix (Sanofi Winthrop); Levaquin (Ortho-McNeil); Quixin (Sanofi Winthrop).


138199-71-0 Relevant articles



Page/Page column 7, (2008/06/13)

This invention relates to a process for ...

Understanding the Dehydration of Levofloxacin Hemihydrate

Eric M. Gorman, Brian Samas, Eric J. Munson

, Journal of Pharmaceutical Sciences, Volume101, Issue9 Special Issue:Dedicated to Professor Valentino Stella September 2012 Pages 3319-3330

In this study, differential scanning calorimetry (DSC), thermogravimetric analysis, Raman spectroscopy, single-crystal and powder X-ray diffraction, and solid-state NMR spectroscopy were used to investigate the transitions that occurred upon dehydration to the anhydrate as well as additional transitions that occurred to the anhydrous material upon heating/cooling.

Fabrication and evaluation of levofloxacin hemihydrate floating tablet

VT Thakkar, PA Shah, TG Soni, MY Parmar, MC Gohel, TR Gandhi

, Research in Pharmaceutical Sciences

The release rate of levofloxacin hemihydrates from matrices was mainly controlled by the hydrophilic and hydrophobic polymer ratio. Matrix tablet containing 25% HPMC K4M and 15% Gelucire 43/01 (F4 batch) showed a release as target profile. Optimal batch (F4) was selected by regression analysis which followed Higuchi kinetic. Novel mathematical approach was applied to determine the deviation in area under the curve (AUC) between predicated and observed dissolution data which found to be lowest in optimal batch.

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