78964-85-9
- Product Name：Fosfomycin tromethamine
- Molecular Formula：C4H11NO3.C3H7O4P
- Purity：99%
- Molecular Weight：259.196
Product Details:
CasNo： 78964-85-9
Molecular Formula： C4H11NO3.C3H7O4P
Appearance： white or off-white powder
Factory Supply High Purity Fosfomycin tromethamine,Offer 78964-85-9 Cheap Price
- Molecular Weight:259.196
- Appearance/Colour:white or off-white powder
- Vapor Pressure:1.57E-06mmHg at 25°C
- Boiling Point:357 °C at 760 mmHg
- Flash Point:169.7 °C
- PSA：166.58000
- LogP:-1.73000
Fosfomycin tromethamine(Cas 78964-85-9) Usage
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Chemical Properties |
White to off-white powder |
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Uses |
Fosfomycin tromethamine is an oral antimicrobial agent. The conversion of fosfomycin to its tromethamine salt has significantly increased its water solubility, allowing for effective oral administration. |
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Brand name |
Monurol (Zambon). |
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General Description |
Fosfomycin tromethamine is a phosphonic acid bactericidal agent with potent activity against various urinary tract pathogens, particularly Escherichia coli, and Citrobacter, Enterobacter, Klebsiella, Serratia, and Enterococcus spp. |
InChI:InChI=1/C4H11NO3.C3H7O4P/c5-4(1-6,2-7)3-8;1-2-3(7-2)8(4,5)6/h6-8H,1-3,5H2;2-3H,1H3,(H2,4,5,6)/t;2-,3+/m.1/s1
78964-85-9 Relevant articles
Single-Dose Treatment of Acute Cystitis with Fosfomycin Tromethamine
Gary E Stein
Annals of Pharmacotherapy, 1998, Volume 32, Issue 2
A single dose of fosfomycin tromethamine is well absorbed and produces therapeutic concentrations in the urine for 2–4 days. Comparative clinical trials suggest that a single dose of fosfomycin tromethamine 3.0 g is as clinically effective as 7- to 10-day treatment regimens of standard agents used to treat UTIs, such as nitrofurantoin, norfloxacin, and trimethoprim/sulfamethoxazole.
In vitro susceptibility testing procedures for fosfomycin tromethamine
A L Barry, P C Fuchs
Antimicrobial Agents and Chemotherapy Vol. 35, No. 6
Fosfomycin tromethamine, norfloxacin, and trimethoprim-sulfamethoxazole inhibited greater than 90% of 352 bacterial isolates representing 25 different species; trimethoprim and nalidixic acid had narrower spectrums of activity.
Fosfomycin tromethamine. Antibiotic of choice in the female patient: A multicenter study
Abdul Rouf Khawaja,corresponding author Farzana Bashir Khan, Tanveer Iqbal Dar, Arif Hameed Bhat, Mohd Saleem Wani, and Baldev Singh Wazir
Cent European J Urol. 2015; 68(3): 371–375.
Of the 400 patients studied, 98% returned for follow-up. Out of the 304 urinary isolates in Table 2 (ASB and symptomatic LUTS) grown on urinary culture, majority of the isolates were Gram-negative Enterobacteriacae family.
78964-85-9 Upstream products
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855392-18-6
2-amino-2-hydroxymethyl-propane-1,3-diol; hydrogenoxalate
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26016-99-9
phosphomycin disodium salt
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77-86-1
2-amino-2-hydroxymethyl-1,3-propanediol
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