496775-62-3
- Product Name：Eltrombopag olamine
- Molecular Formula：C25H22N4O4·2(C2H7NO)
- Purity：99%
- Molecular Weight：564.6394
Product Details:
CasNo： 496775-62-3
Molecular Formula： C25H22N4O4·2(C2H7NO)
Buy High Quality Eltrombopag olamine 496775-62-3 Competitive Price
- Molecular Formula:C25H22N4O4·2(C2H7NO)
- Molecular Weight:564.6394
- PSA：209.05000
- LogP:3.12780
Unii-4U07F515lg(Cas 496775-62-3) Usage
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InChI:InChI=1/C25H22N4O4.2C2H7NO/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33;2*3-1-2-4/h4-13,26,30H,1-3H3,(H,32,33);2*4H,1-3H2/b27-22-;;
496775-62-3 Relevant articles
QBD-driven HPLC method of eltrombopag olamine: Degradation pathway proposal, structure elucidation, and in silico toxicity prediction
Balaji Jayagopal, Murugesh Shivashankar
Journal of Pharmaceutical and Biomedical Analysis Volume 203, 5 September 2021, 114231
The present research aims to develop and validate a robust analytical method through QbD approach to separate and quantify the eltrombopag olamine degradants those are generated from forced degradation of eltrombopag olamine.
Crystal structure of eltrombopag olamine Form I, (C2H8NO)2 (C25H20N4O4)
James A. Kaduk, James A. Kaduk, Amy M. Gindhart and Thomas N. Blanton
Powder Diffraction>Volume 36 Issue 2
The crystal structure of eltrombopag olamine Form I has been solved and refined using synchrotron X-ray powder diffraction data and optimized using density functional techniques. Eltrombopag olamine crystallizes in the space group P21/n (#14) with a = 17.65884(13), b = 7.55980(2), c = 22.02908(16) Å, β = 105.8749(4)°, V = 2828.665(11) Å3, and Z = 4.
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