105826-92-4
- Product Name：Tropisetron Hcl
- Molecular Formula：C17H20N2O2.HCl
- Purity：99%
- Molecular Weight：320.8138
Product Details:
CasNo： 105826-92-4
Molecular Formula： C17H20N2O2.HCl
Buy Reliable Quality 99% Pure Tropisetron Hcl 105826-92-4 On Stock
- Molecular Formula:C17H20N2O2.HCl
- Molecular Weight:320.8138
- Vapor Pressure:3.09E-08mmHg at 25°C
- Melting Point:283-285 ºC
- Boiling Point:448.5 ºC at 760 mmHg
- Flash Point:225 ºC
- PSA：41.90000
- LogP:2.83000
Tropisetron hydrochloride(Cas 105826-92-4) Usage
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Description |
Tropisetron hydrochloride (Tropisetron Hcl) is a pharmaceutical compound formed by combining equimolar amounts of tropisetron and hydrogen chloride. It is a potent, synthetic, and biologically active substance primarily utilized as a selective 5-HT3 receptor antagonist. Tropisetron hydrochloride is commonly employed as an antiemetic agent to manage postoperative nausea and vomiting, as well as the emetogenic side effects induced by cancer chemotherapy. It is available in the form of hard gelatin capsules for oral administration and intravenous injections. |
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Uses |
As a selective 5-HT3 receptor antagonist, tropisetron hydrochloride functions by blocking the action of serotonin (5-HT) at the 5-HT3 receptors. By inhibiting these receptors, tropisetron hydrochloride suppresses nausea and vomiting triggered by various stimuli, including chemotherapy and surgical procedures. |
InChI:InChI=1/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,18H,6-9H2,1H3;1H
105826-92-4 Relevant articles
Oxaliplatin: A review of preclinical and clinical studies
Hanaa A. Abdel Messih,Rania A. H. Ishak,Ahmed S. Geneidi &Samar Mansour
, Drug Development and Industrial Pharmacy Volume 43, 2017 - Issue 6
The study suggests the applicability of statistical modeling as a promising tool for prediction of ethosomal characteristics. The ethanolic vesicles were considered as novel potential nanocarriers for accentuated transdermal Tropisetron HCl (TRO) delivery.
Study on the interaction of tropisetron hydrochloride and l-tryptophan by spectrofluorimetry and its analytical application
Xiashi Zhu, Aiqin Gong, Baosheng Wang, Suhai Yu
, Journal of Luminescence Volume 128, Issue 11, November 2008, Pages 1815-1818
A new method to determine tropisetron hydrochloride with l-tryptophan in the medium with pH=9.0 was studied, which is based on the fluorescence quenching effect of tropisetron hydrochloride on l-tryptophan. The fluorescence quenching mechanism and various factors influencing fluorescence quenching were discussed.
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