1405-10-3
- Product Name：Neomycin Sulphate
- Molecular Formula：C23H46N6O13.3(H2SO4)
- Purity：99%
- Molecular Weight：908.88
Product Details:
CasNo： 1405-10-3
Molecular Formula： C23H46N6O13.3(H2SO4)
Appearance： White powder
Factory Supply High Purity Neomycin Sulphate,Factory Sells 1405-10-3 Low Price
- Molecular Formula:C23H46N6O13.3(H2SO4)
- Molecular Weight:908.88
- Appearance/Colour:White powder
- Vapor Pressure:0mmHg at 25°C
- Melting Point:>187°C (dec.)
- Refractive Index:56 ° (C=10, H2O)
- Boiling Point:1046.1oC at 760 mmHg
- Flash Point:586.5oC
- PSA：436.09000
- LogP:-4.26550
Neomycin sulfate(Cas 1405-10-3) Usage
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Description |
Neomycin Sulfate is not a steroid; it is an antibiotic belonging to the aminoglycoside group. It is primarily used to reduce the risk of infection during bowel surgery and to manage symptoms of hepatic coma. Additionally, it is employed as an antibiotic cream to treat bacterial skin infections such as cuts, wounds, and minor burns. |
| Uses | Regarding safety, Neomycin Sulfate does come with certain warnings. Neurotoxicity can manifest as symptoms like numbness, skin tingling, muscle twitching, and convulsions. Importantly, the risk of hearing loss may persist even after discontinuation of the drug. Moreover, like many medications, Neomycin Sulfate poses risks to fetal development and should be avoided during pregnancy unless the benefits clearly outweigh the potential harm. |
InChI:InChI=1/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6-,7+,8-,9+,10+,11+,12+,13-,14-,15+,16+,17+,18+,19+,20+,21+,22+,23-;/m1./s1
1405-10-3 Relevant articles
Formulation and evaluation of neomycin sulphate ointment containing natural wound healing agent Curcuma longa
Akanksha D1*, Vikas G1 , Neetesh K. J1 , Shailendra S2 , Neelam B1 , Dinesh K. J1
International Journal of Pharmaceutical Sciences and Drug Research 2009; 1(2): 116-118
Present investigation was to develop novel ointment formulation in combination of natural wound healing agent curcuma longa, which is reported to possess wound healing and anti-bacterial activities. Combination of neomycin sulphate and curcuma longa is good rational, where curcuma longa produces synergistic wound healing effect with neomycin sulphate. Formulations containing fixed concentration (0.5 %) of neomycin sulphate and 3 %, 4 % and 5 % of curcuma longa were prepared. To assess the efficacy of formulations anti-bacterial activity, rheology, stability, spreadability and other physical characteristics were evaluated. The results obtained were encouraging and formulation containing neomycin sulphate (0.5 %) with 5 % of curcuma longa was found better than other formulations.
Improved high-performance liquid chromatographic method for simultaneous determination of neamine, neomycin B and neomycin C in neomycin sulphate
Per Helboe, Sonja Kryger
Journal of Chromatography A Volume 235, Issue 1, 22 January 1982, Pages 215-220
A fast and reliable isocratic high-performance liquid chromatographic method suitable for simultaneous determination of the main component and impurities in neomycin sulphate is elaborated. Neomycin B and the related substances are separated as their 2,4-dinitrophenyl derivatives on a Zorbax SIL column using 1,2- dichloroethane-heptane-methanol-water-diethylamine (790:15:55:3.6:1.5) as the eluent. The method is compared to the commonly used microbiological method for quantitating neomycin.
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