128-08-5
- Product Name:N-Bromosuccinimide
- Molecular Formula:C4H4BrNO2
- Purity:99%
- Molecular Weight:177.985
Product Details:
CasNo: 128-08-5
Molecular Formula: C4H4BrNO2
Appearance: white to off-white powder
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Buy Quality N-Bromosuccinimide,Sale 128-08-5 On Stock
- Molecular Formula:C4H4BrNO2
- Molecular Weight:177.985
- Appearance/Colour:white to off-white powder
- Vapor Pressure:0.107mmHg at 25°C
- Melting Point:173- 176°C
- Refractive Index:1.606
- Boiling Point:221.4 °C at 760 mmHg
- PKA:-2.78±0.20(Predicted)
- Flash Point:87.7 °C
- PSA:37.38000
- Density:2.042 g/cm3
- LogP:0.38320
N-Bromosuccinimide(Cas 128-08-5) Usage
Description |
N-Bromosuccinimide is preferred over molecular bromine (Br2) due to its ease of handling and controlled release of bromine radicals. Anthracene, for instance, can be selectively brominated at position 9 using NBS in a radical process, highlighting its utility in achieving specific modifications in complex organic molecules. |
Chemical Properties |
white to light yellow crystalline powder |
Uses |
N-Bromosuccinimide (NBS) is an organic compound widely utilized as a brominating agent in various organic synthesis reactions. It is a convenient source of bromine radicals, making it valuable in radical bromination and electrophilic addition reactions. NBS is characterized by its high reactivity and structural features that facilitate the cleavage of Br⁺ ions. |
InChI:InChI=1/C4H4BrNO2/c5-6-3(7)1-2-4(6)8/h1-2H2
128-08-5 Relevant articles
Incompatibilities between N-Bromosuccinimide and Solvents
Sumio Shimizu*, Yoshiaki Imamura, and Tatsuo Ueki
, Org. Process Res. Dev. 2014, 18, 2, 354–358
Incompatibilities between N-bromosuccinimide (NBS) and solvents were examined by measuring the heat of reaction by an advanced reactive system screening tool (ARSST) and a reaction calorimeter (RC1e). The ARSST experiments showed that amides, THF, and toluene solutions require consideration of incompatibilities with NBS. Isothermal analyses by RC1e revealed accurate heats of incompatibilities and the autocatalytic behaviors of the incompatibilities.
Organic Synthesis Using Sodium Bromate. II. A Facile Synthesis of N-Bromo Imides and Amides Using Sodium Bromate and Hydrobromic Acid (or Sodium Bromide) in the Presence of Sulfuric Acid
Fujisaki, Shizuo,Hamura, Satoshi,Eguchi, Hisao,Nishida, Akiko
, p. 2426 - 2428 (1993)
The reaction of imides and amides in wat...
Triptycenyl Sulfide: A Practical and Active Catalyst for Electrophilic Aromatic Halogenation Using N-Halosuccinimides
Nishii, Yuji,Ikeda, Mitsuhiro,Hayashi, Yoshihiro,Kawauchi, Susumu,Miura, Masahiro
supporting information, p. 1621 - 1629 (2020/02/04)
A Lewis base catalyst Trip-SMe (Trip = t...
Oxidations and Dehydrogenations with N-Bromosuccinimide and Related N-Haloimides.
Robert Filler
, Chem. Rev. 1963, 63, 1, 21–43
… results of their detailed studies on the application of N-bromosuccinimide for allylic brominations. … 68, 70) described the selective oxidation of steroid alcohols by N-bromosuccinimide. …
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