128-08-5

  • Product Name:N-Bromosuccinimide
  • Molecular Formula:C4H4BrNO2
  • Purity:99%
  • Molecular Weight:177.985
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Product Details:

CasNo: 128-08-5

Molecular Formula: C4H4BrNO2

Appearance: white to off-white powder

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Buy Quality N-Bromosuccinimide,Sale 128-08-5 On Stock

  • Molecular Formula:C4H4BrNO2
  • Molecular Weight:177.985
  • Appearance/Colour:white to off-white powder 
  • Vapor Pressure:0.107mmHg at 25°C 
  • Melting Point:173- 176°C 
  • Refractive Index:1.606 
  • Boiling Point:221.4 °C at 760 mmHg 
  • PKA:-2.78±0.20(Predicted) 
  • Flash Point:87.7 °C 
  • PSA:37.38000 
  • Density:2.042 g/cm3 
  • LogP:0.38320 

N-Bromosuccinimide(Cas 128-08-5) Usage

Description

N-Bromosuccinimide is preferred over molecular bromine (Br2) due to its ease of handling and controlled release of bromine radicals. Anthracene, for instance, can be selectively brominated at position 9 using NBS in a radical process, highlighting its utility in achieving specific modifications in complex organic molecules.

Chemical Properties

white to light yellow crystalline powder

Uses

N-Bromosuccinimide (NBS) is an organic compound widely utilized as a brominating agent in various organic synthesis reactions. It is a convenient source of bromine radicals, making it valuable in radical bromination and electrophilic addition reactions. NBS is characterized by its high reactivity and structural features that facilitate the cleavage of Br⁺ ions.

InChI:InChI=1/C4H4BrNO2/c5-6-3(7)1-2-4(6)8/h1-2H2

128-08-5 Relevant articles

Incompatibilities between N-Bromosuccinimide and Solvents

Sumio Shimizu*, Yoshiaki Imamura, and Tatsuo Ueki

, Org. Process Res. Dev. 2014, 18, 2, 354–358

Incompatibilities between N-bromosuccinimide (NBS) and solvents were examined by measuring the heat of reaction by an advanced reactive system screening tool (ARSST) and a reaction calorimeter (RC1e). The ARSST experiments showed that amides, THF, and toluene solutions require consideration of incompatibilities with NBS. Isothermal analyses by RC1e revealed accurate heats of incompatibilities and the autocatalytic behaviors of the incompatibilities.

Organic Synthesis Using Sodium Bromate. II. A Facile Synthesis of N-Bromo Imides and Amides Using Sodium Bromate and Hydrobromic Acid (or Sodium Bromide) in the Presence of Sulfuric Acid

Fujisaki, Shizuo,Hamura, Satoshi,Eguchi, Hisao,Nishida, Akiko

, p. 2426 - 2428 (1993)

The reaction of imides and amides in wat...

Triptycenyl Sulfide: A Practical and Active Catalyst for Electrophilic Aromatic Halogenation Using N-Halosuccinimides

Nishii, Yuji,Ikeda, Mitsuhiro,Hayashi, Yoshihiro,Kawauchi, Susumu,Miura, Masahiro

supporting information, p. 1621 - 1629 (2020/02/04)

A Lewis base catalyst Trip-SMe (Trip = t...

Oxidations and Dehydrogenations with N-Bromosuccinimide and Related N-Haloimides.

Robert Filler

, Chem. Rev. 1963, 63, 1, 21–43

… results of their detailed studies on the application of N-bromosuccinimide for allylic brominations. … 68, 70) described the selective oxidation of steroid alcohols by N-bromosuccinimide. …

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