What is the Ciclopirox?

Ciclopirox is white or light-yellow powder, while it's Molecular Formula is C12H17NO2. white or light-yellow powder Ciclopirox (Penlac) is a synthetic antifungal agent. Ciclopirox (Penlac) is used for topical dermatologic treatment of superficial mycoses. Ciclopirox (Penlac) is most useful against Tinea versicolor. [1] In a study conducted to further elucidate ciclopir

What is the CAS number for Ciclopirox?

The CAS number of Ciclopirox is 29342-05-0.

What is the Ciclopirox?

Ciclopirox is white or light-yellow powder, while it's Molecular Formula is C12H17NO2. white or light-yellow powder Ciclopirox (Penlac) is a synthetic antifungal agent. Ciclopirox (Penlac) is used for topical dermatologic treatment of superficial mycoses. Ciclopirox (Penlac) is most useful against Tinea versicolor. [1] In a study conducted to further elucidate ciclopir

What is the CAS number for Ciclopirox?

The CAS number of Ciclopirox is 29342-05-0.

Product Class

29342-05-0

Product Name：Ciclopirox
Molecular Formula：C₁₂H₁₇NO₂
Purity：99%
Molecular Weight：207.272

Inquiry

Product Details:

CasNo： 29342-05-0

Molecular Formula： C₁₂H₁₇NO₂

Appearance： white or light-yellow powder

Buy High Grade Ciclopirox 29342-05-0,Wholesale 29342-05-0 Safe Transportation

Molecular Formula:C12H17NO2
Molecular Weight:207.272
Appearance/Colour:white or light-yellow powder
Vapor Pressure:2.71E-06mmHg at 25°C
Melting Point:144 °C
Refractive Index:1.582
Boiling Point:350 °C at 760 mmHg
PKA:6.25±0.58(Predicted)
Flash Point:165.5 °C
PSA：42.23000
Density:1.193 g/cm³
LogP:2.44170

Ciclopirox(Cas 29342-05-0) Usage

Description	Ciclopirox is a topical antimycotic agent utilized in the treatment of fungal infections affecting the fingernails and toenails. It belongs to the class of medications known as antifungals and works by inhibiting the growth of nail fungus. Unlike many other antifungal agents, ciclopirox is a hydroxypyridone compound, not related to azoles or other typical antifungal classes.
Uses	Ciclopirox is primarily used to treat fungal infections of the fingernails and toenails, which may manifest as nail discoloration, splitting, and pain. It is commonly prescribed alongside regular nail trimming as part of a comprehensive treatment regimen. The medication effectively combats infections caused by various fungi, including dermatophytes, yeasts, and molds. Moreover, it demonstrates activity against certain azole-resistant Candida species and some bacteria.
Originator	Fungirox Esmalte, UCI-Farma
Definition	ChEBI: A cyclic hydroxamic acid that is 1-hydroxypyridin-2(1H)-one in which the hydrogens at positions 4 and 6 are substituted by methyl and cyclohexyl groups, repectively. A broad spectrum antigfungal agent, it also exhibits antibacterial acti ity against many Gram-positive and Gram-negative bacteria, and has anti-inflammatory properties. It is used a a topical treatment of fungal skin and nail infections.

InChI:InChI=1/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3

29342-05-0 Relevant articles

Ciclopirox Recent Nonclinical and Clinical Data Relevant to its Use as a Topical Antimycotic Agent

Alessandro Subissi, Daniela Monti, Giuseppe Togni & Federico Mailland

Drugs, Volume 70, pages 2133–2152, (2010)

As a general conclusion, although less effective than some oral antimycotic agents in various indications, ciclopirox compares very well in terms of the benefit/risk ratio due to its excellent tolerability and complete absence of serious adverse effects.

The antitumor activity of the fungicide ciclopirox

Hongyu Zhou, Tao Shen, Yan Luo, Lei Liu, Wenxing Chen, Baoshan Xu, Xiuzhen Han, Jia Pang, Chantal A. Rivera, Shile Huang

International Journal of Cancer, Volume127, Issue10 15 November 2010 Pages 2467-2477

To assess the antitumor effect of Ciclopirox(CPX), human breast cancer MDA-MB231 xenografts were established in BALB/c nu/nu mice. When tumors reached <200 mm3, mice were divided randomly into CPX treatment group and control group (5 mice/group). Subsequently, mice were treated daily by oral gavages with CPX (25 mg/kg) prepared in a solution (4% ethanol, 5.2% Tween 80 and 5.2% PEG 400) or vehicle control.