19387-91-8
- Product Name：Tinidazole
- Molecular Formula：C8H13N3O4S
- Purity：99%
- Molecular Weight：247.275
Product Details:
CasNo： 19387-91-8
Molecular Formula： C8H13N3O4S
Appearance： solid
Factory Supply Wholesale Tinidazole 19387-91-8 Efficient Transportation
- Molecular Formula:C8H13N3O4S
- Molecular Weight:247.275
- Appearance/Colour:solid
- Vapor Pressure:1E-10mmHg at 25°C
- Melting Point:117-121°C(lit.)
- Refractive Index:1.599
- Boiling Point:528.4 °C at 760 mmHg
- PKA:2.30±0.34(Predicted)
- Flash Point:273.4 °C
- PSA：106.16000
- Density:1.43 g/cm3
- LogP:2.13840
Tinidazole(Cas 19387-91-8) Usage
|
Pharmacology and mechanism of action |
Similar to metronidazole. |
|
Description |
Tinidazole is an antibiotic medication used to treat various types of infections caused by protozoa, including trichomoniasis, giardiasis, and amebiasis. It is also effective in treating certain vaginal infections, such as bacterial vaginosis. Tinidazole is sold under the brand name Tindamax and is widely used against protozoan infections. |
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Contraindications |
Tinidazole should not be taken together with alcohol. |
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Uses |
Tinidazole is a structural analogue of metronidazole and acts as an antiprotozoal agent. It works by interfering with the DNA of the microorganisms, leading to their death and subsequent resolution of the infection. |
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Clinical Use |
Tinidazole has been used for over two decades in Europe and developing countries, demonstrating established efficacy and tolerability in treating various protozoal infections. Tinidazole is approved by the FDA for the treatment of trichomoniasis, giardiasis, and intestinal and extraintestinal E. histolytica infections, indicating its safety and efficacy for these indications. |
InChI:InChI=1/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3
19387-91-8 Relevant articles
Tinidazole: A nitroimidazole antiprotozoal agent
PharmD, BCPS Horatio B. Fung 1, PharmD Thien-Ly Doan 2
Clinical Therapeutics Volume 27, Issue 12, December 2005, Pages 1859-1884
Relevant information was identified through a search of MEDLINE (1966–August 2005), Iowa Drug Information Service (1966–August 2005), and International Pharmaceutical Abstracts (1970–August 2005) using the terms tinidazole, Fasigyn, and nitroimidazole.
Selective Late-Stage Oxygenation of Sulfides with Ground-State Oxygen by Uranyl Photocatalysis
Li, Yiming,Rizvi, S. Aal-e-Ali,Hu, Deqing,Sun, Danwen,Gao, Anhui,Zhou, Yubo,Li, Jia,Jiang, Xuefeng
supporting information, p. 13499 - 13506 (2019/08/21)
Oxygenation is a fundamental transformat...
Single-dose tinidazole for the treatment of giardiasis
P Speelman
Antimicrobial Agents and Chemotherapy Vol. 27, No. 2
In the first trial 33 randomly selected patients were treated with tinidazole (50 mg/kg of body weight to a maximum of 2 g) or metronidazole (60 mg/kg of body weight to a maximum of 2.4 g) in a single oral dose. Patients were followed for 4 weeks after the end of therapy for the presence of G.
Tinidazole for the treatment of vaginal infections
Michael D Nailor &Jack D Sobel
Expert Opinion on Investigational Drugs Volume 16, 2007 - Issue 5
Ongoing, as yet incomplete, studies directly comparing the clinical efficacy of metronidazole and tinidazole for bacterial vaginosis should clarify the status of tinidazole; however, cure rates are unlikely to be significantly different. Although uncommon, high-level trichomonal metronidazole resistance can be reliably cured by using tinidazole, which is an invaluable advantage.
19387-91-8 Upstream products
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19387-91-8 Downstream products
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