1075240-43-5

Product Details:

CasNo： 1075240-43-5

Molecular Formula： C36H48N4O10S

Appearance： White to yellow solid

Delivery Time： 2 weeks after order

Throughput： 100KG/Month

Purity： 99%

Synonyms: QTH11; Omadacycline p-Toluenesulfonate; Amadacycline P-toluene sulfonate; Omadacycline tosylater; 10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepiner; Omadacyeline tosylate
Solubility: Soluble in DMSO
Water Solubility: H2O: 2mg/mL, clear

Description: 
Omadacycline (tosylate)  is a semisynthetic tetracycline-class antibacterial agent, which has been designated by some as a “new-generation tetracycline” or “the first in a new class of aminomethylcyclines.” Omadacycline has been structurally modified to provide effectiveness against certain strains of bacteria that have mechanisms to resist the action of older tetracyclines. The new agent binds to the 30S ribosomal unit, blocks bacterial protein synthesis, and is generally bacteriostatic[1]. Omadacycline tosylate has broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate has been studied in acute bacterial skin and skin structure infections, community-acquired pneumonia and urinary tract infections.

Uses:
Omadacycline (tosylate) is a new type of 9-aminomethylcycline drug, which is a semi-synthetic compound obtained by modifying chemical groups on the basis of minocycline. The modification can help omacycline overcome bacterial resistance. Pharmacological properties, expand the antibacterial spectrum, and improve the pharmacokinetic properties.

Biological Activity:
Omadacycline (tosylate) is an aminecycline antibiotic with antibacterial activity against Gram-positive and negative aerobic bacteria and some anaerobic bacteria.