Product Class

120511-88-8

Inquiry

CasNo： 120511-88-8

Molecular Formula： C15H18N2O

Appearance： White to Off-White Solid

Delivery Time： Prompt from stock

Packing： Bottle

Throughput： 10g/Month

Purity： 99%

5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile Chemical Properties

Melting point	150-160℃
Boiling point	382.3±37.0 °C(Predicted)
density	1.084
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	14.34±0.10(Predicted)
color	White to Off-White
InChI	InChI=1S/C15H18N2O/c1-14(2,9-16)12-5-11(8-18)6-13(7-12)15(3,4)10-17/h5-7,18H,8H2,1-4H3
InChIKey	PLEAQICJSGOGID-UHFFFAOYSA-N
SMILES	C1(C(C)(C)C#N)=CC(CO)=CC(C(C)(C)C#N)=C1

Safety Information

MSDS Information

5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile Usage And Synthesis

Uses	2-[3-(Cyanodimethylmethyl)-5-hydroxymethylphenyl]-2-methylpropionitrile (Anastrozole EP Impurity E ) is an impurity of Anastrozole (A637425), an aromatase inhibitor which functions as an antineoplastic (1,2). Anastrozole is used in post-menopausal women with advanced breast cancer.
Definition	ChEBI: 2-[3-(2-cyanopropan-2-yl)-5-(hydroxymethyl)phenyl]-2-methylpropanenitrile is an alkylbenzene.

5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile Preparation Products And Raw materials