What is the NBI 56418NA?

NBI 56418NA is , while it's Molecular Formula is C32H29F5N3NaO5. Elagolix Sodium is a novel uracil phenylethylamine that acts as potent human gonadotropin-?releasing hormone receptor (hGnRH-?R) antagonist.

What is the CAS number for NBI 56418NA?

The CAS number of NBI 56418NA is 832720-36-2.

What is NBI 56418NA (832720-36-2) used for?

Elagolix is an antagonist of the gonadotropin-releasing hormone receptor (GnRHR; Ki = 0.9 nM in a radioligand binding assay). It is selective for GnRHR over the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 56 μM) as well as a panel of 100 receptors, ion channels, enzymes, and transporters (IC50s = >10 μM). Elagolix inhibits GnRH-induced inositol phosphate production in RBL-1 cells expressing human GnRHR (IC50 = 1.5 nM). In vivo, elagolix (30 mg/kg) suppresses production of luteinizing hormone in castrated male cynomolgus macaques. Formulations containing elagolix have been used in the treatment of endometriosis.InChI:InChI=1/C32H30F5N3O5.Na/c1-19-28(21-11-6-14-26(45-2)29(21)34)30(43)40(18-25(20-9-4-3-5-10-20)38-16-8-15-27(41)42)31(44)39(19)17-22-23(32(35,36)37)12-7-13-24(22)33;/h3-7,9-14,25,38H,8,15-18H2,1-2H3,(H,41,42);/q;+1/p-1/t25-;/m0./s1

What is the NBI 56418NA?

NBI 56418NA is , while it's Molecular Formula is C32H29F5N3NaO5. Elagolix Sodium is a novel uracil phenylethylamine that acts as potent human gonadotropin-?releasing hormone receptor (hGnRH-?R) antagonist.

What is the CAS number for NBI 56418NA?

The CAS number of NBI 56418NA is 832720-36-2.

What is NBI 56418NA (832720-36-2) used for?

Elagolix is an antagonist of the gonadotropin-releasing hormone receptor (GnRHR; Ki = 0.9 nM in a radioligand binding assay). It is selective for GnRHR over the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 56 μM) as well as a panel of 100 receptors, ion channels, enzymes, and transporters (IC50s = >10 μM). Elagolix inhibits GnRH-induced inositol phosphate production in RBL-1 cells expressing human GnRHR (IC50 = 1.5 nM). In vivo, elagolix (30 mg/kg) suppresses production of luteinizing hormone in castrated male cynomolgus macaques. Formulations containing elagolix have been used in the treatment of endometriosis.InChI:InChI=1/C32H30F5N3O5.Na/c1-19-28(21-11-6-14-26(45-2)29(21)34)30(43)40(18-25(20-9-4-3-5-10-20)38-16-8-15-27(41)42)31(44)39(19)17-22-23(32(35,36)37)12-7-13-24(22)33;/h3-7,9-14,25,38H,8,15-18H2,1-2H3,(H,41,42);/q;+1/p-1/t25-;/m0./s1

Product Class

Building Blocks
Reference Compounds & Impurities
Natural products
APIs & Intermediates

Anti-Coagulant & Heart System

Anti-Fungal

Anti-Psychotic & Epileptic & Insomnia

Anti-Tumor & Anti-Cancer

Anti-AID & Anti-RA & ITP

Respiratory & Gastrointestinal

Anti-Virus & Anti-Biotic

CKD & HD & cGVHD & Eyes & NASH

For Men & Women & PNH

Anti-Migraine & Parkinsonian & PNP

Anti-Diabetic & Anti-Hypertensive

Others

intermediate

Peptides API
Antibody-drug Conjugates (ADCs)
Others

832720-36-2

Product Name：Elagolix Sodium
Molecular Formula：C32H29F5N3NaO5
Purity：99%
Molecular Weight：653.5715

Inquiry

Product Details:

CasNo： 832720-36-2

Molecular Formula： C32H29F5N3NaO5

Chinese Factory Supply Elagolix Sodium 832720-36-2 Cheap Price Safe Transportation

Molecular Formula:C32H29F5N3NaO5
Molecular Weight:653.5715
PSA：105.39000
LogP:4.59120

Relevant Products

Fezolinetant
CAS：1629229-37-3
Nilotinib Hcl
CAS：923288-90-8
Clotrimazole
CAS：23593-75-1

News Center